Viviendo en comunidad, envejeciendo de forma saludable / Vivendo em comunidade, envelhecendo de forma saudável / Living in community, healthy aging

INTRODUCCIÓN: Es notable el aumento de la población anciana brasileña. Los avances en investigaciones y tecnologías han contribuido al aumento de la expectativa de vida, reducción de la mortalidad y mejora de la calidad de vida. OBJETIVOS: Elaborar el perfil de los ancianos participantes e identificar los impactos en la salud del anciano y el estilo de vida derivado de la participación en actividades en la Universidade Abierta a Personas Ancianas (UnAPA). MÉTODO: Estudio descriptivo y exploratorio cuanti-cualitativo. Se utilizó un cuestionario que contenía datos sociodemográficos/socioeconómicos, condición de salud/comorbilidades, además de preguntas abiertas relacionadas al cambio en la salud y estilo de vida tras participación en las actividades de la UnAPA e importancia del grupo en la salud y en la vida del anciano. RESULTADOS: El estudio apuntó prevalencia del sexo femenino, promedio de edad 73 años. La mayoría reside en Vitória/ES, casa propia, casados, renta proveniente de jubilación, nivel superior completo e informaron que después de frecuentar las actividades en la UnAPA notaron cambios en su salud, pasaron a sentir más disposición para vivir, salir de casa, más alegría. En cuanto al estilo de vida dijeron que tuvo influencia en la práctic de actividades que estimulan la memoria, pasaron a leer con más frecuencia, practicar ejercicios físicos, se volvieron más sociables, con mejora del sueño, entre otros beneficios. CONCLUSIÓN: Se constató que los ancianos notan cambios em su salud, estilo de vida, y relaciones. Repercutiendo en una mejor calidad de vida

INTRODUÇÃO: É notável o aumento da população idosa brasileira em que avanços em pesquisas e tecnologias têm contribuído para o aumento da expectativa de vida, redução da mortalidade e melhoria da qualidade de vida. OBJETIVOS: Elaborar o perfil dos idosos participantes e identificar os impactos na saúde do idoso e estilo de vida decorrente da participação em atividades na Universidade Aberta à Pessoas Idosas (UnAPI). MÉTODO: Estudo descritivo e exploratório quanti-qualitativo. Utilizou-se questionário contendo dados sociodemográficos / socioeconômicos, condição de saúde / comorbidades, além de perguntas abertas relacionadas à mudança na saúde e estilo de vida após participação nas atividades da UnAPI e importância do grupo na saúde e na vida do idoso. RESULTADOS: Evidenciou prevalência do sexo feminino, casadas, média de 73 anos de idade, sendo expressivo a residência em Vitória/ES, em casa própria, com renda proveniente de aposentadoria e nível superior completo. Após frequentarem as atividades na UnATI, os participantes informaram mudanças em sua saúde, passando a sentir mais disposição para viver, sair de casa e ter mais alegria. Quanto ao estilo de vida relataram influência para a prática de atividades que estimulam a memória, passaram a ler com mais frequência, praticar exercícios físicos, tornaram-se mais sociáveis, com melhora do sono e outros benefícios. CONCLUSÃO: Constatou-se que os idosos notaram mudanças em sua saúde, estilo de vida, bem como nos relacionamentos, repercutindo beneficamente na qualidade de vida

INTRODUCTION: It is remarkable the increase of the Brazilian elderly population. Advances in research and technology have contributed to increase life expectancy, reduce mortality and improve quality of life. OBJECTIVES: Elaborate the profile of the elderly participants of the research and identify the health impacts of the elderly due to their participation in activities at the Universidade Aberta à Pessoas Idosas (UnAPI). METHOD: Descriptive and exploratory quantitative-qualitative study. Inclusion criteria adopted: age > 60 years, having joined UnAPI for 6 months, being enrolled in the activities and having attended more than once. A questionnaire containing socio-demographic/socioeconomic data, health condition/comorbidities, and open-ended questions related to the change in health and lifestyle after participation in the activities of UnATI and the importance of the group in health and life were used. RESULTS: The study showed female prevalence, mean age 73 years. Most of them reside in Vitória/ES, their own home, married, income from retirement, complete upper level and reported that after attending activities at UnATI noticed changes in their health, they began to feel more disposed to live, leave home, more joy. Regarding lifestyle, they said they had great influence, started to practice activities that stimulate memory, read more often, practice physical exercises, become more sociable, improve sleep, among other benefits. CONCLUSION: It was observed that the elderly notice changes, mainly in health, lifestyle, and relationships. Promoting better quality of life

Tributyltin chloride disrupts aortic vascular reactivity and increases reactive oxygen species production in female rats.

Organotin compounds, such as tributyltin (TBT), are environment contaminants that induce bioaccumulation and have potential toxic effects on marine species and mammals. TBT have been banned by the International Maritime Organization in 2003. However, the assessment of butyltin and metal contents in marine sediments has demonstrated high residual levels of TBT in some cases exceeding 7000 ng Sn g-1. The acceptable daily intake (ADI) level for TBT established by the World Health Organization is 0.5 µg/kg bw/day is based on genotoxicity, reproduction, teratogenicity, immunotoxicity, and mainly neurotoxicity. However, their effect on the cardiovascular system is not well understood. In this study, female rats were exposed to 0.5 µg/kg/day of TBT for 15 days with the goal of understanding the effect of TBT on vascular function. Female Wistar rats were treated daily by gavage and divided into control (n = 10) and TBT (n = 10) groups. The aortic rings were incubated with phenylephrine in both the presence and absence of endothelium. The phenylephrine concentration-response curves were generated by exposing endothelium-intact samples to NG-nitro-L-arginine methyl ester (L-NAME), apocynin, superoxide dismutase (SOD), catalase, tiron, and allopurinol. Acetylcholine (ACh) and sodium nitroprusside (SNP) were used to evaluate the relaxation response. Exposure to TBT reduced serum 17ß-estradiol E2 levels and increased vascular reactivity. After incubation with L-NAME, the vascular reactivity to phenylephrine was significantly higher. Apocynin, SOD, catalase, and tiron decreased the vascular reactivity to phenylephrine to a significantly greater extent in TBT-treated rats than in the control rat. The relaxation induced by ACh and SNP was significantly reduced in TBT rats. Exposure to TBT induced aortic wall atrophy and increased superoxide anion production and collagen deposition. These results provide evidence that exposing rats to the current ADI for TBT (0.5 µg/kg) for 15 days induced vascular dysfunction due to oxidative stress and morphological damage and should be considered an important cardiovascular risk factor.